Oligopeptide-1

Best

Peptide

Oligopeptide-1 at a glance

  • Plant-derived cell-rejuvenating peptide
  • Targets skin's elasticity network
  • Visibly firms skin from within
  • Classified as a skin-conditioning agent
  • May be used as an umbrella term for oligopeptide derivatives
  • Potential benefits include collagen and elastin support

Oligopeptide-1 description

Oligopeptide-1 is a synthetic peptide consisting of the skin-beneficial amino acids glycine, histidine and lysine. “Oligopeptide-1” can also be used as a catch-all ingredient name for various oligopeptide derivatives. As this category of peptides has expanded over time, specific INCI names have been introduced for differentiation. However, the umbrella term “oligopeptide-1” may still be used. While oligopeptide-1 is generally categorized as a “skin-conditioning agent,” specific oligopeptide-1 derivatives offer more targeted anti-aging benefits. One such standout is _Nicotiana benthamiana_ hexapeptide-40 sh-oligopeptide-1, which is a plant-derived pro-collagen peptide that specializes in improving skin’s elasticity and reducing the look of wrinkles. Documented benefits of other oligopeptides are quite varied and include visible fading of dark spots, skin-soothing action, and potential to manage breakout-prone skin. Use levels of oligopeptide-1 in skin care are 1–2% when it is supplied in a water-based blend (which means the actual concentration of the peptide is much lower since these ingredients typically work in the parts per million level). For more detailed information on specific oligopeptide derivatives, please refer to the related ingredient listings.

Oligopeptide-1 references

  • Polymers, November 2022, pages 1–13
  • Cosmetics, November 2020, pages 1–16
  • Biotechnology Reports, September 2020, pages 1–10
  • Experimental Dermatology, August 2012, pages 569–575; and May 2012, pages 563–568

Peer-reviewed, substantiated scientific research is used to assess ingredients in this dictionary. Regulations regarding constraints, permitted concentration levels and availability vary by country and region.

Ingredient ratings

Best

Proven and supported by independent studies. Outstanding active ingredient for most skin types or concerns.

Good

Necessary to improve a formula's texture, stability, or penetration.

Average

Generally non-irritating but may have aesthetic, stability, or other issues that limit its usefulness.

Bad

There is a likelihood of irritation. Risk increases when combined with other problematic ingredients.

Worst

May cause irritation, inflammation, dryness, etc. May offer benefit in some capability but overall, proven to do more harm than good.

unknown

We couldn't find this in our ingredient dictionary. We log all missing ingredients and make continuous updates.

Not rated

We have not yet rated this ingredient because we have not had a chance to review the research on it.